• Product Name: 35150 Cold and Hot Plate
• Order number: tlyon000395
• Brand Name: Ugo Italy

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35150- Cold and Hot Plates - New Version

The new version of the hot and cold plates can be set at any experimental temperature between -5 and 65 ° C. Can be used as a traditional hot plate for rapid and accurate drug screening of anesthetics and analgesics; It can also be used for cold pain testing to study cold receptors and cold touch induced pain. There are two working modes to choose from: testing at a fixed temperature or when the temperature rises/falls (RAMP). An optional additional hot plate can be connected to the main unit to increase experimental flux.
35150- The appearance of the cold and hot plate is similar to the previous version, providing equal reliability and adding innovative technology! Equipped with brand new and user-friendly software. Through the new software, operators can easily manage and schedule experiments on their personal computers, and upload them to the hot and cold plates via USB flash drives. The software will automatically classify data, and based on the experimental results settings, users can add information before and after testing. The result is presented as a tree structure, similar to a custom layout, and the column chart can be dragged as needed. Configuration and data can be exported to Text, Excel, or PDF formats for further saving.
The new version of cold and hot plate provides remote diagnosis and Internet access. The experiment can be set up on a 4 "3 touch screen and monitored. The temperature control equipment has significantly improved, and the temperature changes faster during the experimental process!

characteristic	advantage
Large adjustable temperature range (-5--65 ° C)	It is an ideal tool for studying hyperalgesia and cold pain
Optional additional hot plate, two temperature modes to choose from	Double the experimental flux and allow animals to familiarize themselves with the experimental environment before the experiment
New version of software	Easy to store and transfer experimental data

Specifications:

Working temperature:- From 5 ° C to 65 ° C, every 0.1 ° C
Testing method: foot switch
Operation mode: Temperature fixed mode or temperature change mode.
Software: A brand new and convenient software that can set up experiments and manage experimental results
Control: 4 "3 touch screen can be used to set and monitor experiments
Data transfer: via USB memory drive

Universal voltage: Temperature regulation range:	85-264V，50-60Hz -5--65°C
Resolution of time and temperature readings:	0.1 s, 0.1°C
Specifications: Weight: Load capacity: Packaging specifications:	25 * 37 * 47cm including one animal restraint device 8.0kg About 12kg 65*34*28cm

enclosure:

35150 cold/hot plate, standard packaging, including:
35150-001 Controller/Display and Board
35100-286 animal restraint device, for mice and rats, height 25cm
35150-320 Bonder Cover
35150-302 instruction manual (in USB flash drive)
37215-303 foot switch
E-AU 041 flash drive
E-WP 008 power cord

optional
Additional traditional hot plate 35150-002 as an optional accessory; This independent unit can be used during the habit phase before testing.
35150-002 Additional Hot Plate

reference:

• C.V. Möser: ” TANK-Binding Kinase 1 (TBK1) Modulates Inflammatory Hyperalgesia by Regulating MAP Kinases and NF-κB Dependent Genes” J. Neuroinflammation 12:100, 2015
• W. Kallenborn-Gerhardt et alia: ”Nox2-dependent signaling between macrophages and sensory neurons contributes to neuropathic pain hypersensitivity” Pain 55(19): 2161-2160, 2014
• D. Piomelli et alia: ”Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism” Nature NSC, 2010
• M. Sakurai et alia: ”Oxaliplatin-induced neuropathy in the rat: involvement of oxalate in cold hyperalgesia but not mechanical allodynia”. Pain 147 (2009) 165-174
• L. Yu et alia: ”Effects of calcitonin gene-related peptide-(8-37) on withdrawal responses in rats with inflammation” EJP 347 (1998) 275-282