Self administration of MED self-administration research system
The self-administration research system is a commonly used method in behavioral pharmacology research. It utilizes the positive enhancing effects of certain drugs and controls them under certain conditions. After animals perform the prescribed actions and steps in the experimental program, they can obtain certain incentive operations, establishing a connection between action and reward, thereby simulating some situations of human drug abuse.
This system involves inserting a silicone tube into the cranial vein of a rat through surgery, which will pass subcutaneously to the top of the head. The silicone tube is then fixed to the skull of the rat through a sleeve, and the other end of the sleeve is connected to a medication bottle. The animal can obtain food, water, or addictive drugs caffeine and nicotine by learning to press the rod. When the rat steps on the pressure rod, the switch is turned on, and medication is automatically injected into the rat's body. When animals become addicted and switch to physiological saline instead of drugs, they will repeatedly stomp on them in order to obtain the drugs. The computer will automatically record parameters such as the duration of animal addiction and the number of animal stampedes, or inject dopamine blockers into mice while injecting drugs, and after a period of time, stop administering drugs to observe animal behavior.
This system can use software to program and control experimental steps to achieve different experimental purposes, and can also freely add audio stimulation, light stimulation, and electrical stimulation to verify that negative stimulation can once again stimulate addicts' psychological craving for drugs.
This system is a commonly used model for studying animal learning and motivational behavior, and the establishment of its own drug delivery system provides a comprehensive scientific research tool for qualitative and quantitative analysis and evaluation of drug psychological dependence potential.
Note: This product is mainly used as an experimental instrument for scientific research. Non clinical medical equipment.