CIP cleaning system, commonly known as on-site cleaning system, is widely used for cleaning and purifying production equipment with strict hygiene requirements in the beverage, dairy, juice, alcohol, pharmaceutical industries, etc. Including container bodies, pipelines, pumps, filters, and the entire production line, without the need for manual disassembly or opening, a certain temperature of cleaning solution is sprayed and circulated through a closed pipeline on the inner surface of the equipment within a predetermined time to achieve the purpose of cleaning.

CIP cleaning, also known as cleaning positioning or positioning cleaning. On site cleaning refers to the method of using a cleaning solution of * temperature and * concentration to apply strong force to equipment and devices without dismantling or moving the equipment, to clean the contact surfaces with food and requirements.

CIP online cleaning equipment refers to equipment (tanks, pipelines, pumps, filters, etc.) and the entire production line that, without the need for manual disassembly or opening, sprays and circulates a certain temperature of cleaning solution through a closed pipeline on the inner surface of the equipment within a predetermined time to achieve the purpose of cleaning. It is specifically called CIP online cleaning system (cleaning in place). A stable CIP online cleaning system relies on excellent design, including a complete set of technical systems for equipment, pipelines, operating procedures, cleaning agent formulations, automatic control, and monitoring requirements. Based on the actual situation of the cleaning system, determine the appropriate cleaning procedure, including the determination of cleaning conditions, selection of cleaning agents, and recycling design. And record and print the key parameters and conditions (such as time, temperature, flow rate, conductivity) during the cleaning process as verification of the equipment cleaning process.

The CIP online cleaning system is one of the prerequisites for hygiene standards in pharmaceutical production. It can eliminate cross contamination of active ingredients and eliminate insoluble particles of foreign substances. Reduce or eliminate contamination of drugs by microorganisms and heat sources. The product has the characteristics of high degree of automation, easy operation, and reasonable price.

2、 CIP cleaning features:

1. Compact design, easy installation, maintenance, and debugging; Stable and reliable performance, with a modular structure composed of functional blocks that can be separated, automatically selected, and operated with touch screen prompts, making it intuitive and easy to understand.

2. Remove drug residues, prevent microbial contamination, and avoid interference between batches;

3. Comply with GMP requirements and verify the cleaning process;

4. Can rationalize production plans and improve production capacity;

5. Following the programmed steps can effectively prevent operational errors, improve cleaning efficiency, reduce labor intensity, save labor, and improve drug quality compared to hand washing operations;

6. Reduce cleaning costs and minimize the consumption of water, cleaning agents, and steam;

7. Can increase the service life of machine components;

8. Safe and reliable, the equipment does not need to be disassembled;

3、 CIP cleaning composition

The CIP online cleaning system mainly consists of single or multiple cleaning solution storage tanks and pipelines, distributors, booster pumps, reflux pumps, pneumatic control valves, acid-base metering pumps, plate heat exchangers, temperature controllers, conductivity detectors, liquid level controllers, PLC touch screens, and control cabinets.

4、 Working principle of CIP cleaning

According to the adjustable program, the CIP cleaning system automatically configures the cleaning solution, which is then transported and circulated through the pneumatic control valve, booster pump, and reflux pump to complete the entire cleaning process, including cleaning, discharge, and recovery. The control system composed of conductivity, temperature controller, acid-base metering pump, and PLC touch screen has achieved automatic online cleaning. It can detect and record the time, flow rate, and conductivity of each cleaning program, print and output them, and ensure that the temperature and concentration of the cleaning solution are automatically constant during the corresponding cleaning process. The system cleaning structure has a conductivity meter for automatic detection and display.

5、 CIP cleaning program

Taking the beverage industry as an example, its cleaning procedures are as follows:

Wash for 3-5 minutes with hot water at room temperature or above 60 ℃; Alkaline washing for 10-20 minutes, 1% -2% solution, 60 ℃ -80 ℃; Wash for 5-10 minutes in the middle with clean water below 60 ℃; Wash for 3-5 minutes with clean water.

Wash for 3-5 minutes with hot water at room temperature or above 60 ℃; Alkali wash for 5-10 minutes, 1% -2% solution, 60 ℃ -80 ℃, intermediate wash for 5-10 minutes, clear water below 60 ℃, sterilize for 10-20 minutes, hot water above 90 ℃.

The guarantee of cleaning flow rate is actually to ensure the flow rate of the cleaning solution during cleaning, thereby generating a certain mechanical effect, that is, to enhance the impact force by improving the turbulence of the fluid and achieve a certain cleaning effect.

6、 Cleaning equipment, CIP cleaning equipment, CIP online cleaning equipment:

CIP cleaning is widely used in industries such as food, dairy, pharmaceuticals, and biochemistry, mainly engaged in the cyclic cleaning of liquid equipment and pipelines. The entire cleaning process does not require disassembly and is a closed cleaning method. Improve cleaning efficiency, reduce labor intensity, save labor, and improve drug quality; Reduce the consumption of water, cleaning agents, and steam;