Double Chamber System
This system provides another option for long-term tracking research, where the experimental animals are in a state of wakefulness but unable to move freely. This system uses a double chamberer to measure the airflow in the animal's head and chest separately, and calculates the specific airway resistance (SRaw) and specific airway conductivity (SGaw). This system can be used for non-invasive airway mechanics research. An atomized drug delivery system can be installed.

characteristic: It can observe multiple animals simultaneously and is suitable for long-term tracking and research. SRaw and SGaw parameters are highly correlated with airway resistance and compliance measured by innovative methods. The preparation for animal experiments is more complex than whole-body plethysmography. Double chambered plethysmography cavity in rats

Available technical parameters:
Specific airway resistance
Specific airway conductance
Breath frequency
Tidal volume
Total volume breathed
Minute ventilation
Inspiratory time
Expiratory time
Peak inspiratory flow
Peak expiratory flow
End inspiratory pause
End expiratory pause
Relaxation time
Expiratory flow at 50% volume (EF50)
Others

FinePointe NAM System for non-invasive airway dynamics research
New typeFinePointe NAMThe system originates fromDouble ChamberThe system has been optimized and redesigned on the basis of inheriting its original characteristics, which is very suitable for research on asthma, COPD, and other diseases. Animals do not require anesthesia or tracheal intubation surgery, and can be tracked for a long time to study the response and efficacy of the same animal to drugs or therapies. Special airway resistance (SRaw) and special airway conductance (SGaw) are widely recognized non-invasive animal lung function monitoring indicators in the academic community. It is a widely recognized non-invasive detection standard in academia in the past thirty years. It calculates the special airway resistance sRaw by detecting the phase difference between nasal airflow and chest airflow, and is an ideal indicator widely accepted as an alternative to invasive detection. The patent feature of FinePointe NAM lies in changing the sealing method of the front and rear chambers, replacing the original sealing at the neck of the animal with a sealing at the back of the nose. At the same time, the method of restricting the animal's position has been changed to use the bone protrusion behind the animal's ear and a U-shaped clip for fixation. Its advantage is that it reduces the time required for skilled operators to load an animal from half an hour to about an hour in the old system to within 30 seconds, and no longer uses a push rod to press against the animal's buttocks, avoiding respiratory abnormalities caused by compression of the animal's position.

Main features: No anesthesia or tracheal intubation required, animals are awake but restricted in movement (non-invasive testing); Detect direct physiological indicators such as sRaw specific airway resistance, sGaw specific airway conductivity, tidal volume, and EF50 that reflect small airway resistance; Fully automatic calibration, avoiding the tedious work and uncertainty of manual daily calibration; The digital to analog conversion (A/D), preamplifier, sensor, atomization drug control, and bias current meter are integrated into the same workbench, with a more compact and concise structure, making installation and rearrangement very convenient; AllayTM's patented animal fixation and nasal sealing make it extremely convenient to fit animals. Animals will no longer have difficulty breathing due to tight neck restraints, and their adaptation time will be greatly shortened; • Standard atomization drug delivery function; Suitable for long-term follow-up research; • Easy to expand. The standard configuration includes simultaneous testing of four animals, and the NAM group can detect up to 12 animals simultaneously through USB connection. FinePointe system software provides one-stop services from data monitoring to experimental reports.

	The FinePointe NAM 2 chamber system provided for budget limited users occupies a desktop area of 45x40cm. The standard configuration is a 4-chamber model, with a desktop area of 90 x 40 cm. The NAM system can change animal species simply by changing the Chamber.
	The NAM data analysis module provides real-time nasal airflow, chest airflow, and volume waveforms, mainly outputting the following detection data indicators: sRaw special airway resistance, sGaw special airway conductivity, F respiratory rate, TV tidal volume, TI inhalation time, TE exhalation time, PIF inhalation peak, PEF exhalation peak, Frc functional residual volume, EF50, MV, etc.

Note: This product is mainly used as an experimental instrument for scientific research. Non clinical medical equipment.

Origin: United States

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