main features
Small animal ex vivo cardiac perfusion, cardiac retrograde perfusion system
A system includes two modes: constant voltage and constant current system
• Built in precision flowmeter
Data is directly output to computer software without the need to connect to a physiological signal acquisition system
Easy to operate, easy to clean, and easy to maintain
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Myoheart Langendorff ex vivo cardiac perfusion system is used for small animal ex vivo cardiac perfusion research.
The Myoheart ex vivo cardiac perfusion system is a practical and easy-to-use instrument that studies cardiac function by retrograde perfusion of the heart. Using cutting-edge technology, the structure design of the ex vivo cardiac perfusion system is more compact, and all measurement and monitoring operations can be completed through a touch screen.
The instrument is equipped with a built-in pressure transducer, which can monitor pressure changes in real-time in constant current mode. In addition, selecting a flow meter can measure changes in aortic flow rate in constant pressure mode.
By selecting different configuration modules, parameters such as aortic flow rate, perfusion liquid oxygen concentration, and heart surface temperature can be measured. Other controllable experimental parameters include perfusion pressure, perfusion flow rate, temperature, buffer temperature, BPM (pacemaker), and left ventricular pressure.
The software can record and display up to 18 parameters. By using a driver, digital signal data can be directly output to a computer without the need to connect any physiological signal acquisition system for signal conversion.
Touchscreen capable of displaying data and controlling devices
Option Modules
Flow meter module
ECG/Pacer module
PH module
Oxygen concentration module
Left ventricular pressure module
Why is Myoheart a professional ex vivo cardiac perfusion system
There are already a large number of imported and domestically produced ex vivo cardiac perfusion systems purchased by domestic research institutions. But how many companies can professionally and standardly complete ex vivo cardiac perfusion experiments. I'm afraid most of the experiments were discounted. The main reason for this is the lack of specialized ex vivo cardiac perfusion equipment, and the system is pieced together; The experimental process lacks professional and standardized technical guidance.
Traditional ex vivo cardiac perfusion systems often have hardware and software produced by different manufacturers. There is no specialized integration in the software. The overall control and measurement of the equipment are very inconvenient and inaccurate.
Let's take a look at how Myoheart integrates all hardware and software.
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Professional ECG electrodes and pacemakers |
Left ventricular pressure measurement module (including catheter and left ventricular pressure balloon) |
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Oxygen and pH sensors |
Peristaltic pump |
Simply explain the above figure: Traditional ex vivo cardiac perfusion systems are rarely equipped with professional electrocardiographic electrodes and pacemakers. Myoheart's ECG electrodes are contact electrodes. Can maintain reliable contact with the heart even when the heart is beating. And it does not cause damage to the surface of the heart. The following figure shows the details of the electrode. Such meticulous consideration is given to the fixation of electrodes in contact with the heart in all directions.
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AgCl ECG Contact Electrode |
Placement of ECG electrodes |
Electrocardiogram waveform measured by ex vivo cardiac perfusion system
Left ventricular pressure (LVP) measurement is another important indicator of measurement in the ex vivo cardiac perfusion system. The left ventricular pressure measurement module has been meticulously equipped with a pressure balloon. Although this balloon is small, it often affects the success or failure of pressure measurement. Purchasing imported pressure balloons separately is time-consuming, expensive, and laborious. Some domestic customers also make it themselves. It is difficult to ensure consistent stability of the balloon effect. In addition, the module is also equipped with dedicated conduits, integrated with pressure sensors, and even equipped with a filling syringe. I can't help but say that I have a deep understanding of the experimenter's heart. Another noteworthy feature is the integrated pressure sensor. Sensors are fixed in specific positions on the device. It will not be arbitrarily fixed like traditional ex vivo cardiac perfusion systems, and the pressure height difference will produce inconsistent test results.
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Left ventricular pressure measurement waveform
The Myoheart ex vivo cardiac perfusion system not only integrates the required hardware, but also has corresponding settings, control, or measurement units for the integrated hardware in the software. Making the experimental process more automated while ensuring the accuracy of the experiment.
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Flow and pressure control |
Peristaltic pump speed control |
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Pacemaker settings |
gain setting |
Another issue that users are most concerned about is having a professional ex vivo cardiac perfusion system equipment. How to conduct actual experiments? The operation of the instrument goes without saying. The system has a complete operation manual. Users can clearly understand every detail of device operation. At the same time, the manufacturer also has specific technical guidance materials for the surgical and experimental preparation of ex vivo hearts. Provide customers with standardized and specific experimental operation process guidance. The following images are some surgical guidance pictures.
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The perfect manufacturing process, like many Danish products, is pleasing to the eye. Equipped with integrated modular hardware configuration, providing corresponding control measurement for software. Provide detailed technical guidance on experimental details. Myoheart is currently the most comprehensive and excellent ex vivo cardiac perfusion system.
Related products:
Traditional ex vivo cardiac perfusion system (Langendorff, working heart)
Cardiomyocyte isolation perfusion system
Note: This product is mainly used as an animal experimental instrument for scientific research. Non clinical medical equipment.