Polyethylene glycol pipeline three-stage emulsifier

Polyethylene glycol high-speed emulsifier, polyethylene glycol derivative high-speed emulsifier, polyethylene glycol technology,PEGylation technology is an advanced pharmaceutical macromolecule modification technique. The connection between polyethylene glycol molecules and drug molecules can increase the relative molecular weight of drugs, achieve the effects of prolonging drug efficacy, reducing toxicity, and increasing drug water solubility. PEGylation technology is an important means to improve the clinical efficacy of drugs.

The application of medicinal polyethylene glycol derivatives as safe and side effect free polymer materials in the field of medical devices is also flourishing. Due to the safe degradation and absorption of PEG products in the body without generating rejection reactions, medical devices prepared from PEG products can be widely used in materials such as wound adhesion, hemostasis, leakage prevention, and adhesion prevention in various surgical procedures on the human body. The market prospects are extremely broad.
Non toxic, non irritating, slightly bitter in taste, with good propertiesWater solubilityAnd it has good compatibility with many organic components. They have excellent lubricity, moisturization, dispersibility, adhesives, anti-static agents, and softeners, and are widely used in industries such as cosmetics, pharmaceuticals, chemical fibers, rubber, plastics, papermaking, painting, electroplating, pesticides, metal processing, and food processing.

Polyethylene glycol and polyethylene glycol fatty acid esters are widely used in the cosmetics and pharmaceutical industries. Due to the excellent properties of polyethylene glycol, including water solubility, non volatility, inertness, mildness, lubricity, and the ability to wet, soften, and provide a pleasant aftertaste to the skin. Polyethylene glycol with different relative molecular weight fractions can be selected to alter the viscosity, moisture absorption, and microstructure of the product. Polyethylene glycol (Mr<2000) with low relative molecular weight is suitable for use as a wetting agent and consistency regulator, for creams, lotion, toothpaste, shaving cream, etc., and also for hair care products that are not cleaned, giving hair silky luster. Polyethylene glycol (Mr>2000) with high relative molecular weight is suitable for lipstick, deodorant stick, soap, shaving soap, foundation make-up and beauty cosmetics. Polyethylene glycol is also used as a suspension agent and thickener in cleaning agents. In the pharmaceutical industry, it is used as a matrix for ointments, emulsions, ointments, detergents, and suppositories. Commercial polyethylene glycol (such as Polyethylene Glycol NF, Dow Chemical Co.) suitable for food and drug use is more suitable for cosmetic use. The application of methoxy polyethylene glycol and polypropylene glycol is similar to that of polyethylene glycol.

Polyethylene glycol is widely used in various pharmaceutical preparations, such as injections, topical preparations, ophthalmic preparationsOral administrationPreparation for rectal use. Solid grade polyethylene glycol can be added to liquid polyethylene glycol to adjust viscosity and used for topical ointments; Polyethylene glycol mixture can be used as a suppository base; Polyethylene glycol aqueous solution can be used as a suspension aid or to adjust the viscosity of other suspension media; Polyethylene glycol is used in combination with other emulsifiers to increase emulsion stability. In addition, polyethylene glycol is also used as a film coating agent, tablet lubricant, controlled release material, etc.

The high rotational speed and shear rate of the emulsifier are crucial for obtaining ultrafine suspensions. According to some industry specific requirements, Xide Company has developed the XRS2000 ultra high speed shear homogenizer on the basis of the XR2000 series. Its shear rate can exceed 100.00 rpm, and the rotor speed can reach 40m/s. Within this speed range, turbulence caused by shear forces combined with specially developed motors can reduce the particle size range to the nanometer level. The shear force is stronger, and the particle size distribution of lotion is narrower. Due to its extremely high energy density, no other auxiliary dispersing equipment is required.

XRS2000 imported ultra-high shear high-speed emulsifier
The three-stage high shear dispersion machine is mainly used for the production of micro lotion and ultra-fine suspension lotion. Since three groups of dispersion heads (stator+rotor) in the working chamber work at the same time, after high shearing, the lotion drops are more delicate and the particle size distribution is narrower, so the stability of the generated mixed liquid is better. The three sets of dispersing heads are easy to replace and suitable for different process applications. The different models of machines in this series have the same line speed and shear rate, making it very easy to scale up production. It also meets the CIP/SIP cleaning standards and is suitable for food and pharmaceutical production.

High rotational speed and shear rate are important for obtaining ultrafine suspension lotion. According to some industry specific requirements, its shear rate can exceed 15000rpm, and the rotor speed can reach 44m/s. Within this speed range, turbulence caused by shear forces combined with specially developed motors can reduce the particle size range to the nanometer level. The shear force is stronger, and the particle size distribution of lotion is narrower.

The following is a model table for reference:

Polyethylene glycol pipeline three-stage emulsifier