Transonic T400 series research grade modular blood flow meter from the United States
The T400 series blood flow meter, also known as the Ultrasonic Flowmeter, is the most advanced blood flow testing tool. It can be used for both acute blood flow testing and chronic long-term blood flow monitoring (implantation). It is a substitute for traditional electromagnetic flow meters and ultrasonic Doppler blood flow meters.

The gold standard method for measuring blood flow

Transonic ultrasound flowmeter is a highly sensitive flow testing device suitable for various arterial and venous vessels (ascending aorta, pulmonary artery, coronary artery, carotid artery, renal artery, femoral artery, mesenteric artery, hepatic artery, portal vein, etc.) in various animals (mice, rats, cats, rabbits, dogs, pigs, sheep, etc.). It is also applicable for measuring liquid flow inside various pipelines or through probes (artificial hearts, VAD effect detection, engineering research of medical equipment and pumps, manufacturing flow error testing, etc.). This flowmeter measures absolute flow volume rather than flow velocity or relative flow rate. There are a large number of applied literature in foreign professional journals, which are regarded as the gold standard for blood flow measurement.

Unprecedented sensitivity can fully meet various blood flow tests as small as mice Mouse mesenteric artery blood flow

Can meet the measurement of blood flow in conscious exercise animals Monitoring of femoral artery blood flow in mice during exercise treadmill

Reliable ultrasound transit time technology, unprecedented flow signal accuracy, and multi-channel modular design can be mixed and matched to meet your laboratory needs.

T402/T403 main chassis
There are two models of 400 series host boxes:

T402 dual channel blood flow box: can accommodate 2 blood flow modules T403 three channel blood flow box: can accommodate 3 blood flow modules

The main chassis is a new type of enclosure that can provide power support for the inserted blood flow module. The rear panel has a signal processor that outputs analog signals from the module. The multi-channel screw hole interface block can be connected to data acquisition and recording devices. The main chassis can be equipped with one blood flow module, two modules (T402), or three modules (T403)

Flow module of ultrasonic flowmeter

TS420 vascular blood flow module This module is suitable for acute and chronic measurement of various blood vessels. For example, aorta, coronary artery, carotid artery The Transonic system features convenient plug and play operation modes PS series and PR series acute/chronic vascular blood flow probes can be used PAX series 4-sensor cardiac output probes can be used. Ultra small nanoprobes probes can be used. Accurate measurement of blood flow less than 1ml/min. The extended ultrasound frequency range of 450KHz-14.4MHz can adapt to the smallest probe size A bandwidth of 160Hz can accurately represent the hemodynamics of high heart rate mice. It can display blood flow digitally. The analog table displays the voltage value corresponding to the blood flow The front panel is equipped with a socket for the chronic probe calibration key.
TS410 pipeline flow module This module is suitable for flow measurement in experimental pipelines. For example, artificial heart and extracorporeal circulation, medical equipment and pump design, Blood flow testing during product production process Low signal-to-noise ratio has become a thing of the past for pipeline flow measurement ME-PXL series 4-sensor pipeline flow sensor can be used ME-PXN series 4-sensor internal flow-through flow sensor can be used The editable gain can be used for calibration under different flowability and temperature conditions Editable alarms: threshold alarms for low/high limit received signals. Easy to read luminous digital LCD display

Technical parameters of traffic module:
LED average blood flow display
Signal strength optical band display
One time trigger key zeroing
Low traffic range can increase sensitivity by 4 times.
0.1, 10, 40, 160 Hz filtering settings
Front panel BNC analog signal output
Back panel 8 analog output signal interface block. Including: pulsating flow rate, average flow rate, signal quality, acoustic phase
External synchronization
Voltage range+-5volts
Ultrasonic frequency range; 450KHz-14.4MHz

Ultrasonic flowmeter flow probe
High precision vascular blood flow probe (used with TS420 module)
The traffic range can range from mice to pigs
Acute application or chronic implantation, suitable for arteries and veins.
Multiple structures can meet the needs of various animal model experiments.
Unparalleled precision and iconic high-resolution blood flow waveforms.

	Ultra small NANOPROBES probe 0.5-0.7 millimeters The smallest type of probe. The acute measurement application is equipped with a handle, which can stably fix the probe on the anesthetized rats and mice through a micro manipulator. Chronic implantable probes can be used for the study of conscious animals.
	PS and PR series probes 1-20 millimeters Standard acute probe. Customized implantable probes with special specifications
	PAX series cardiac output blood flow probe 8-36 millimeters Suitable for acute blood flow measurement of the ascending aorta and pulmonary artery, and providing non laminar or turbulent reviews.
	V-series microcirculation probe only suitable for acute use 0.5-0.7 millimeters The Transonic System is a unique probe series suitable for small blood vessels less than 0.7 millimeters. Unique design of ultrasonic mirror reflection, sturdy and durable. The placement of the blood flow probe is stable and requires the use of more ultrasound coupling agents than ultra small probes.
	PMP series handle type blood flow probe 2-14 millimeters Intraoperative measurements for animal experiments prior to clinical surgery should be conducted using equipment that is compatible with the clinical surgical environment.

Extracorporeal flow probe (for TS410 module)

ME-PXN series internal flow-through flow sensor

In vitro organ research Traffic phantoms, loop models Any application that requires high-precision traffic sensitivity

Has enhanced accuracy and wide dynamic range. The PXN internal flow-through flow sensor combined with experimental tubing can measure the absolute value of blood flow or other liquid flow. The new four sensor design provides accurate flow measurement. Stable measurement of pulsating flow rate within the range of 1ml/min-100 liters/min. This sensor can calibrate and edit four different liquids at different temperatures.

ME-PXL series clamp type flow sensor

Artificial heart and VAD effect testing Engineering research on medical equipment and pumps Manufacturing and flow error testing.

PXL clamp type flow sensor clamps the outer surface of laboratory tubing. There is no contact with internal liquid substances. The ME-PXL series flow sensor can handle four different liquids. Calibrate temperature and pipeline materials. The size of the sensor is determined by the outer diameter of the pipeline. The standard ME-PXL sensor size is a multiple of 1/16 inch.


Literature on the use of ultrasound flowmeter(For a large number of different animal and vascular literature, please call to request)
Cardiac output measurement by arterial pressure waveform analysis during optimization of biventricular pacing after cardiac surgery.
Booth JH, Quinn TA, Richmond ME, Cabreriza SE, Weinberg AD, Johnston T, Spotnitz HM. From the *Departments of Surgery, daggerBiomedical Engineering, double daggerPediatrics, section signBiostatistics, and paragraph signAnesthesiology, Columbia Univer, ASAIO J.. 2009 Sep 17 (Human, Aorta, Acute)

Spontaneous baroreflex control of heart rate versus cardiac output: altered coupling in heart failure.
Sala-Mercado JA, Ichinose M, Hammond RL, Coutsos M, Ichinose T, Pallante M, Iellamo F, O\'Leary DS. Department of Physiology, Wayne State University School of Medicine, Detroit, MI 48201, USA, Am J Physiol Heart Circ Physiol.. 2008 Mar; 294(3):H1304-9. (Dog, Aorta, Ascending, Chronic)

Clozapine and olanzapine, but not haloperidol, reverse cold-induced and lipopolysaccharide-induced cutaneous vasoconstriction.
Blessing WW, Department of Physiology, Centre for Neuroscience, Flinders University, Bedford Park, SA, 5042, Australia. Psychopharmacology (Berl).. 2004 Oct; 175(4):487-93 (Rabbit, Auricular a., Acute)

Bronchial Blood Flow during Changes in Inhaled Oxygen & CO2 Concentration in Conscious Sheep
Stothert, J.C., Basadre, J.O., Gbaanador, G.B.M., Flynn, J.T., Traber, D.L, Circulatory Shock. Vol. 36, p. 120-26, 1992 (Sheep, Bronchial a., Chronic)

Lung Edema Formation Following Inhalation Injury: Role of the Bronchial Blood Flow
Abdi, S., Herndon, D.N., Traber, L., Ashley, K.D., Stothert, J.C, Journal of Applied Physiology. Vol. 71, No. 2, p. 727-734, 1991 (Sheep, Bronchial a., Chronic)

Note: This product is mainly used as an experimental instrument for scientific research. Non clinical medical equipment.