VCU traumatic brain injury instrument-Global supplier

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VCU traumatic brain injury instrument

Traumatic brain injury (TBI) is the most common disease in neurosurgery and the leading cause of disability and death in trauma patients. Studying the

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Traumatic brain injury (TBI) is the most common disease in neurosurgery and the leading cause of disability and death in trauma patients. Studying the changes in neurobiology, neuropathophysiology, and other aspects after brain injury can provide assistance in exploring effective brain protection treatments, which will help improve the survival rate and quality of life of patients with traumatic brain injury. Therefore, establishing various traumatic brain injury models that are easy to observe and apply intervention factors, have good control, can be graded, replicated, and conform to the characteristics of human traumatic brain injury is currently a research hotspot in traumatic brain injury.
The VCU animal brain injury instrument can be divided into cell injury control instrument (CIC), electronic cortical contusion impact instrument (eCCI), and hydraulic impact injury instrument (FPI). These three products have been widely used in traumatic brain injury research centers worldwide and are currently the only gold standard for creating traumatic brain injury models. At the same time, FPI injury instrument can also be applied to ophthalmic injury models, and CIC cell injury instrument can be applied to the production of other types of cell injury models.

Hydraulic impact damage instrument (FPI)

The Fluid Percussion Injury Instrument is designed and manufactured by VCU University for the study of neural trauma mechanisms. Becoming a widely used instrument for global research on nerve trauma, the basic components adopt the most advanced Power coating process technology, and the aluminum components have been electroplated to avoid oxidation and can be used for a long time. The hydraulic shock brain injury device can produce consistent and repetitive resultsHydraulic impact damage(FPI)。

System advantages:
Can easily eliminate gas saturation.
The angle scale allows for easy observation of the impact angle.
Integrated pressure reference force output for easy calibration. Can output precise impact pressure.
Equipped with high-precision pressure sensors

Cell Damage Control Instrument (CIC)

The Cell Injury Controller II adopts electronic control and is suitable for brain derived cell culture samples or other in vitro culturesThe stretchability of cells（strain-induced trauma）Damage modelmake. After injury, research can be conducted in areas such as neurobiology, morphology, physiology, and drug intervention. The cell damage control device uses Flexcell Int'l corp's patented tissue culture system. The cell damage control device sends compressed gas to each culture chamber on average to cause tensile damage to the cultured tissue, and the severity of the damage depends on controlling the amount of gas entering and leaving the sealed culture chamber. The peak pressure of the culture chamber is simultaneously recorded, which can be used to accurately indicate the pressure value that causes tensile cell damage. The Cell Damage Control Instrument (CIC II) can be paired with Flex I ® 29.45cm2 cultivation travels I (cell damage control device for early VCU) or BioFlex ® 57.75cm2 cultivation trips. Because damaged cells may die or repair due to the types of cells used, the degree of damage, and the condition of the culture, VCU's Cell Damage Control Instrument (CIC II) is well suited for studying damage reactions such as cell damage, repair, death, and drug intervention.

Electronic cerebral cortex contusion impactor (eCCI)

The electric cortical contusion impactor designed by VCU University is mainly aimed atCortical contusion modelIt is the most popular tool for creating injury models in neural injury research institutions. The components of the electronic cerebral cortex contusion impact instrument (eCCI) include a sturdy aluminum frame, animal platform, impact controller, and impact head. The animal platform can be used in conjunction with various stereotaxic devices. The eCCI electronic cerebral cortex contusion impactor uses advanced linear motors to drive the impactor head, and the impact parameters are controlled by a controller to achieve different degrees of damage. The component part of the impact head contains sensors that can determine the velocity, impact depth, and impact stop. These impact parameters can be fully replicated.
Compared with the traditional Feeney's free fall epidural impact method, it has the following advantages:
It can accurately and continuously control the impact velocity, and obtain parameters such as actual impact depth and dwell time. Instead of impacts with significant differences in weight. Due to the precise control of impact velocity and the acquisition of actual impact result parameters, the eCCI electronic cerebral cortex contusion impactor can accurately replicate contusion injury models. Reduce animal mortality. Make the experimental process more intuitive and controllable.

Note: This product is mainly used as an experimental instrument for scientific research. Non clinical medical equipment.

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